Proto-oncogene tyrosine-protein kinase Src

Proteins and Enzymes

Proto-oncogene tyrosine-protein kinase Src, usually called c-Src, is a non-receptor tyrosine kinase protein encoded in humans by the SRC gene. It belongs to the Src family kinases and contains SH2, SH3 and tyrosine kinase domains. c-Src phosphorylates particular tyrosine residues in other tyrosine kinases and helps regulate embryonic development and cell growth. Increased activity is suggested to be linked to cancer progression.

Encoded by: SRC gene in humans
Protein domains: SH2, SH3 and tyrosine kinase domains
Discovered by: J. Michael Bishop and Harold E. Varmus

Sources and credits

Article: Proto-oncogene tyrosine-protein kinase Src (English Wikipedia)
Wikidata: Q21109354
Text: Card text is adapted from the English Wikipedia article by an automated summary. Wikipedia content is available under CC BY-SA 4.0; see the article history for its contributors. CC BY-SA 4.0 · Article history and contributors
Illustration: By National Center for Biotechnology Information, U.S. National Library of Medicine. Public domain · File page on Wikimedia Commons
National Center for Biotechnology Information, U.S. National Library of Medicine, NCBI's Genome Decoration Page.
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