Exon junction complex
ConceptGenetics and Molecular Biology
Protein complex deposited on spliced messenger RNA
1.00Common
Common
Exon junction complex
- Genetics and Molecular Biology
- Cell Biology
- Proteins and Enzymes
The exon junction complex (EJC) is a protein complex formed on pre-messenger RNA where two exons are joined during RNA splicing. It is deposited during splicing and transported into the cytoplasm, where it contributes to post-transcriptional regulation of messenger RNA. The EJC influences translation, surveillance, localization and m6A methylation of spliced mRNA. Its stable heterotetramer core provides a platform for factors involved in the mRNA pathway.
- Forms at
- Junctions of exons joined during RNA splicing
- Core components
- eIF4A-III, an ATP analog, Magoh and Y14
- Cellular transport
- Deposited during splicing, then transported to the cytoplasm
Sources and credits
Sources and credits
- Article
- Exon junction complex (English Wikipedia)
- Wikidata
- Q3717361
- Text
- Card text is adapted from the English Wikipedia article by an automated summary. Wikipedia content is available under CC BY-SA 4.0; see the article history for its contributors. CC BY-SA 4.0 · Article history and contributors
- Illustration
- By Danmen. CC BY-SA 3.0 · File page on Wikimedia CommonsDanmen, Andersen et alModifications: Resized and converted to WebP
- Popularity
- 7 median daily views (Wikimedia Pageviews API (all-access, user agent))
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