Reverse migration (immunology)

Cell Biology

Reverse migration is a phenomenon in molecular and cell biology in which some neutrophils move away from an inflammation site, against the chemokine gradient, during inflammation resolution. Inflammatory pathways, including hypoxia-inducible factor, can alter neutrophil migration behavior. Reverse migration may help resolve inflammation by removing neutrophils from an injury site, but returning neutrophils may also contribute to systemic infection. Its regulatory mechanisms remain poorly understood.

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Cell type: Neutrophils
Potential benefit: Removal of neutrophils during inflammation resolution
Potential risk: May contribute to spread of systemic infection

Sources and credits

Article: Reverse migration (immunology) (English Wikipedia)
Wikidata: Q7318245
Text: Card text is adapted from the English Wikipedia article by an automated summary. Wikipedia content is available under CC BY-SA 4.0; see the article history for its contributors. CC BY-SA 4.0 · Article history and contributors
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