Tissue-resident memory T cell

A long-lived memory T-cell subset that remains in tissues without recirculating.

A long-lived memory T-cell subset that remains in tissues without recirculating.
Common
Tissue-resident memory T cells, or TRM cells, are a subset of long-lived memory T cells that occupy epithelial, mucosal, and other tissues without recirculating. They occur in sites including the skin, mucosa, lung, brain, pancreas, and gastrointestinal tract. TRM cells are transcriptionally, phenotypically, and functionally distinct from recirculating central memory and effector memory T cells. Their populations are diverse between tissues and within individual tissues, and they protect extralymphoid tissues against infection.
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