High-affinity choline transporter

Proteins and Enzymes

The high-affinity choline transporter, also called solute carrier family 5 member 7, is a human protein encoded by the SLC5A7 gene. It is a cell membrane transporter that carries choline into neurons that synthesize acetylcholine. Hemicholinium-3 inhibits the transporter and can deplete acetylcholine stores. Coluracetam enhances it and can increase cholinergic neurotransmission by enhancing acetylcholine synthesis.

Encoded by: SLC5A7 gene
Function: Carries choline into acetylcholine-synthesizing neurons
Inhibitor: Hemicholinium-3

Sources and credits

Article: Choline transporter (English Wikipedia)
Wikidata: Q18045336
Text: Card text is adapted from the English Wikipedia article by an automated summary. Wikipedia content is available under CC BY-SA 4.0; see the article history for its contributors. CC BY-SA 4.0 · Article history and contributors
Illustration: By National Center for Biotechnology Information, U.S. National Library of Medicine. Public domain · File page on Wikimedia Commons
National Center for Biotechnology Information, U.S. National Library of Medicine, NCBI's Genome Decoration Page.
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